Cancer Genomics & Metabolomics

Oncogenomics is a sub-field of genomics that characterizes cancer-associated or cancer related genes. It focuses mainly on genomic, epigenomic and transcript alterations in cancer. The main concept and idea of oncogenomics is to check new group of oncogenes or tumor suppressor genes that may give new areas of research into cancer diagnosis, predicting clinical outcome of cancers and new targets for cancer therapies. The Gleevec, Herceptin and Avastin are the targeted cancer therapies which gave a new way for oncogenomics to elucidate new targets for cancer treatment. Metabolomics is a newly emerging field of 'omics' research and refers to the complete set of small- molecules metabolites, which gives the systematic study of unique chemical fingerprints that leaves cellular processes behind. The metabolome represents the collection of all metabolites in a biological cell, tissue, organ or organism that are the end products of cellular processes. Metabolic profiling gives an instantaneous snapshot of the physiology of the given cell. One of the challenging aspects of systems biology and functional genomics is to integrate proteomic, transcriptomic, and metabolomic information which provide a better understanding of cellular biology.

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